此外 , 当前肝炎病毒感染者已经有老龄化趋势 , 往往合并多种慢性疾病 , 需要长期服用阿司匹林、他汀类药物 , 而这些药物也可能有一定的防癌作用 。 将来还得靠前瞻性研究 , 专门分析H1抗组胺药到底有多大能耐才行 。
参考文献:
1.Shen Y C, Hsu H C, Lin T M, et al. H1-Antihistamines Reduce the Risk of Hepatocellular Carcinoma in Patients With Hepatitis B Virus, Hepatitis C Virus, or Dual Hepatitis B Virus-Hepatitis C Virus Infection[J]. Journal of Clinical Oncology, 2022.
2.Feng Y M, Feng C W, Lu C L, et al. Cyproheptadine significantly improves the overall and progression-free survival of sorafenib-treated advanced HCC patients[J]. Japanese Journal of Clinical Oncology, 2015, 45(4): 336-342.
3.Hsieh M C, Lee W H, Wu A T H, et al. Cyproheptadine use in hepatocellular carcinoma[J]. American Journal of Cancer Research, 2017, 7(3): 584.
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